Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.58 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.56 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.56 |
| ▸ | UQCRB | P14927 | 1/20 | 0.52 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.52 |
| ▸ | ACLY | P53396 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7588697 | 0.89 | PTGES2 (0.74) | PTGES2KMT2AMEN1MAPTLMNA | |
| SCHEMBL7589492 | 0.84 | PTGES2 (0.56) | PTGES2ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL13875339 | 0.82 | ALDH1A1 (0.71) | ALDH1A1KEAP1KMT2AMEN1TSHR | |
| SCHEMBL16325550 | 0.82 | FFAR4 (0.63) | ALDH1A1KMT2AMEN1MAPTHTT | |
| SCHEMBL13615288 | 0.82 | HSD17B2 (0.57) | PTGES2HSD11B1UQCRBHSD17B2CYP2C9 | |
| SCHEMBL4623054 | 0.82 | ALDH1A1 (0.75) | ALDH1A1KEAP1KMT2AMEN1MAPT | |
| SCHEMBL834586 | 0.82 | ALDH1A1 (0.75) | ALDH1A1KEAP1KMT2AMEN1MAPT | |
| SCHEMBL1116405 | 0.81 | ALDH1A1 (0.74) | ALDH1A1KEAP1KMT2AMEN1MAPT | |
| SCHEMBL30102910 | 0.81 | ALDH1A1 (0.74) | ALDH1A1KEAP1KMT2AMEN1MAPT | |
| SCHEMBL29540970 | 0.81 | KEAP1 (0.68) | PTGES2KEAP1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007112998-A1 | 3-UNSUBSTITUTED N-(ARYL- OR HETEROARVL)-PYRAZOLORI [1,5-A]PYRIMIDINES AS KINASE INHIBITORS | NOVARTIS AG (CH) | 2007-10-11 | — | — | WO | disclosed |