Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | GGPS1 | O95749 | 4/20 | 0.32 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LPAR6 | P43657 | 3/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.32 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.32 |
| ▸ | LPAR5 | Q9H1C0 | 3/20 | 0.32 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.32 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.32 |
| ▸ | FDPS | P14324 | 6/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11664049 | 0.75 | — | — | |
| SCHEMBL1657544 | 0.73 | ALDH1A1 (0.33) | TSHRALDH1A1LMNAHSD17B10MEN1 | |
| SCHEMBL12220685 | 0.72 | TSHR (0.41) | TSHRALDH1A1 | |
| SCHEMBL12220678 | 0.72 | TSHR (0.41) | TSHRALDH1A1 | |
| SCHEMBL26855936 | 0.72 | LPAR3 (0.37) | TSHRTHRBGGPS1SMPD1LPAR6 | |
| SCHEMBL28674433 | 0.71 | TSHR (0.38) | TSHRTHRBGGPS1ALDH1A1LMNA | |
| SCHEMBL3148134 | 0.70 | TSHR (0.46) | TSHRTHRBGGPS1SMPD1ALDH1A1 | |
| SCHEMBL19432796 | 0.70 | TSHR (0.42) | TSHRTHRBGGPS1ALDH1A1LMNA | |
| SCHEMBL20609962 | 0.70 | TSHR (0.42) | TSHRTHRBGGPS1ALDH1A1LMNA | |
| SCHEMBL95578 | 0.70 | TSHR (0.46) | TSHRTHRBGGPS1SMPD1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7288567-B2 | Inhibitors of histone deacetylase | METHYLGENE INC. (CA) | 2007-10-30 | — | — | US | disclosed |