Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1B | O75688 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1783180 | 0.78 | PTPN1 (0.42) | PPM1B | |
| SCHEMBL1783179 | 0.78 | PTPN1 (0.42) | PPM1B | |
| SCHEMBL1659971 | 0.72 | TRPA1 (0.39) | — | |
| SCHEMBL1659972 | 0.72 | TRPA1 (0.39) | — | |
| SCHEMBL14104010 | 0.69 | — | — | |
| SCHEMBL18672298 | 0.67 | GABRP (0.42) | — | |
| SCHEMBL15285517 | 0.67 | GABRP (0.42) | — | |
| SCHEMBL15285518 | 0.67 | GABRP (0.42) | — | |
| SCHEMBL1659678 | 0.66 | TSHR (0.34) | — | |
| SCHEMBL15285674 | 0.66 | TSHR (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7288567-B2 | Inhibitors of histone deacetylase | METHYLGENE INC. (CA) | 2007-10-30 | — | — | US | disclosed |