Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.77 |
| ▸ | OPRM1 | P35372 | 9/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 9/20 | 0.52 |
| ▸ | OGFRL1 | Q5TC84 | 8/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1441135 | 0.99 | MEN1 (0.74) | MEN1KMT2AALDH1A1OPRM1OPRK1 | |
| SCHEMBL1441295 | 0.93 | MEN1 (0.66) | MEN1KMT2AALDH1A1OPRM1OPRK1 | |
| SCHEMBL11372663 | 0.86 | ALDH1A1 (0.76) | MEN1KMT2AALDH1A1OPRM1OPRK1 | |
| SCHEMBL31423075 | 0.82 | ALDH1A1 (0.56) | MEN1KMT2AALDH1A1OPRM1OPRK1 | |
| SCHEMBL5332461 | 0.81 | ALDH1A1 (0.71) | MEN1KMT2AALDH1A1OPRM1OPRK1 | |
| SCHEMBL19335453 | 0.81 | ALDH1A1 (0.71) | MEN1KMT2AALDH1A1OPRM1OPRK1 | |
| SCHEMBL8248062 | 0.80 | KMT2A (0.66) | MEN1KMT2AALDH1A1OGFRL1NPC1 | |
| SCHEMBL11377355 | 0.79 | ALDH1A1 (0.69) | MEN1KMT2AALDH1A1OPRM1OPRK1 | |
| SCHEMBL11639723 | 0.77 | ALDH1A1 (0.61) | MEN1KMT2AALDH1A1OPRM1OPRK1 | |
| SCHEMBL10674838 | 0.76 | ALDH1A1 (0.60) | MEN1KMT2AALDH1A1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2507225-A1 | L -DIHYDRO-2-OXOQUINOLINE COMPOUNDS A 5-HT4 RECEPTOR LIGANDS | Suven Life Sciences Limited (IN) | 2012-10-10 | — | — | EP | claimed |
| WO-2011030349-A1 | L -DIHYDRO-2-OXOQUINOLINE COMPOUNDS A 5-HT4 RECEPTOR LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2011-03-17 | — | — | WO | claimed |
| CN-110115365-A | The adjusting that actinism receptor and relative ligand are carried out | 西诺米克斯公司 | 2019-08-13 | — | — | CN | disclosed |
| EP-2507225-A1 | L -DIHYDRO-2-OXOQUINOLINE COMPOUNDS A 5-HT4 RECEPTOR LIGANDS | Suven Life Sciences Limited (IN) | 2012-10-10 | — | — | EP | disclosed |