Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.44 |
| ▸ | OGFRL1 | Q5TC84 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.43 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.43 |
| ▸ | HTR3B | O95264 | 2/20 | 0.43 |
| ▸ | HTR3A | P46098 | 2/20 | 0.43 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.43 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1441135 | 0.94 | MEN1 (0.74) | MEN1KMT2AALDH1A1PADI4OPRM1 | |
| SCHEMBL1440437 | 0.93 | MEN1 (0.77) | MEN1KMT2AALDH1A1OPRM1OPRD1 | |
| SCHEMBL11372663 | 0.82 | ALDH1A1 (0.76) | MEN1KMT2AALDH1A1PADI4OPRM1 | |
| SCHEMBL31423075 | 0.80 | ALDH1A1 (0.56) | MEN1KMT2AALDH1A1PADI4OPRM1 | |
| SCHEMBL28859816 | 0.76 | MEN1 (0.46) | MEN1KMT2AALDH1A1PADI4OPRM1 | |
| SCHEMBL35212365 | 0.76 | ALDH1A1 (0.74) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL10962357 | 0.76 | ALDH1A1 (0.74) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL10680267 | 0.76 | MEN1 (0.60) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL11377355 | 0.75 | ALDH1A1 (0.69) | MEN1KMT2AALDH1A1OPRM1OPRD1 | |
| SCHEMBL5332461 | 0.74 | ALDH1A1 (0.71) | MEN1KMT2AALDH1A1OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2507225-A1 | L -DIHYDRO-2-OXOQUINOLINE COMPOUNDS A 5-HT4 RECEPTOR LIGANDS | Suven Life Sciences Limited (IN) | 2012-10-10 | — | — | EP | claimed |
| WO-2011030349-A1 | L -DIHYDRO-2-OXOQUINOLINE COMPOUNDS A 5-HT4 RECEPTOR LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2011-03-17 | — | — | WO | claimed |
| EP-2507225-A1 | L -DIHYDRO-2-OXOQUINOLINE COMPOUNDS A 5-HT4 RECEPTOR LIGANDS | Suven Life Sciences Limited (IN) | 2012-10-10 | — | — | EP | disclosed |