Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 11/20 | 0.45 |
| ▸ | NOS1 | P29475 | 11/20 | 0.45 |
| ▸ | NOS2 | P35228 | 8/20 | 0.45 |
| ▸ | HTR6 | P50406 | 4/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | TERT | O14746 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27747783 | 0.79 | NOS3 (0.52) | NOS3NOS1NOS2HTR6RAD52 | |
| SCHEMBL2266718 | 0.78 | CHRNB4 (0.50) | NOS3NOS1NOS2HTR6 | |
| SCHEMBL2265423 | 0.75 | NOS3 (0.50) | NOS3NOS1NOS2HTR6 | |
| SCHEMBL2261749 | 0.74 | NOS3 (0.64) | NOS3NOS1NOS2HTR6 | |
| SCHEMBL2262122 | 0.74 | NOS3 (0.64) | NOS3NOS1NOS2HTR6 | |
| SCHEMBL15178521 | 0.73 | NOS3 (0.61) | NOS3NOS1NOS2HTR6 | |
| SCHEMBL12367568 | 0.72 | NOS3 (0.56) | NOS3NOS1NOS2HTR6 | |
| SCHEMBL2263689 | 0.72 | NOS3 (0.65) | NOS3NOS1NOS2 | |
| SCHEMBL27768895 | 0.70 | CHRNB2 (0.46) | NOS3NOS1NOS2HTR6CHRM3 | |
| SCHEMBL2263181 | 0.69 | NOS3 (0.51) | NOS3NOS1NOS2HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007118314-A1 | 1,5 AND 3,6- SUBSTITUTED INDOLE COMPOUNDS HAVING NOS INHIBITORY ACTIVITY | NEURAXON, INC. (CA) | 2007-10-25 | — | — | WO | disclosed |