Thiobenzoic Acid

Thiobenzoic Acid

SCHEMBL144057

CC(OC(=S)c1ccccc1)c1ccccc1.OC(=S)c1ccccc1

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 1/20 0.44
ALDH1A1 P00352 5/20 0.38
CYP3A4 P08684 2/20 0.38
HSD17B10 Q99714 2/20 0.35
ADRA2C P18825 2/20 0.35
CHRM2 P08172 1/20 0.35
ADRA1A P35348 1/20 0.35
RGS12 O14924 1/20 0.35
GLA P06280 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
PKM P14618 1/20 0.35
ALOX15 P16050 1/20 0.35
TSHR P16473 1/20 0.35
ALOX12 P18054 1/20 0.35
NFKB1 P19838 1/20 0.35
HTR2A P28223 1/20 0.35
CYP2C19 P33261 1/20 0.35
THPO P40225 1/20 0.35
GNAI1 P63096 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27908685 0.94 HCAR2 (0.47) HCAR2ALDH1A1CYP3A4HSD17B10ADRA2C
Thiobenzoic Acid SCHEMBL11610122 0.91 ESR1 (0.42) HCAR2ALDH1A1HSD17B10MAPTMEN1
Thiobenzoic Acid SCHEMBL1525000 0.88 L3MBTL1 (0.44) ALDH1A1CYP3A4HSD17B10CYP2C9PKM
Thiobenzoic Acid SCHEMBL29012058 0.83 ALDH1A1 (0.43) ALDH1A1TSHRHPGDTP53MAPT
Thiobenzoic Acid SCHEMBL476269 0.77 ALDH1A1 (0.40) ALDH1A1TSHRALOX12HPGDTP53
Thiobenzoic Acid SCHEMBL476144 0.77 ALDH1A1 (0.40) ALDH1A1TSHRALOX12HPGDMAPT
Thiobenzoic Acid SCHEMBL476265 0.77 ALDH1A1 (0.40) ALDH1A1TSHRALOX12HPGDTP53
SCHEMBL5839440 0.77 PDCD1 (0.46) ALDH1A1TSHRHPGDTP53MAPT
Isopropylbenzene SCHEMBL29089229 0.77 HTT (0.48) ALDH1A1CYP3A4HSD17B10ADRA2CCHRM2
Isopropylbenzene SCHEMBL5009940 0.77 HTT (0.48) ALDH1A1CYP3A4HSD17B10ADRA2CCHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 223 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023099310-A1 PREPARATION OF HIGH SOLID CONTENT, SURFACTANT-FREE LATEX USING FUNCTIONAL AMPHIPHILIC WATERBORNE MACRO-RAFT AGENT BASF SE (DE) 2023-06-08 WO claimed
CN-108641053-B Thermoplastic elastomers polymerized via reversible addition-fragmentation chain transfer of triglycerides 爱荷华州立大学研究基金会有限公司 2021-04-23 CN claimed
CN-110627934-A Isotactic polypropylene with dithiobenzoic acid alpha-methylbenzyl ester as end group, and preparation method and application thereof 青岛科技大学 2019-12-31 CN claimed
US-20090280430-A1 Method for Manufacturing Toner LG CHEM, LTD. (KR) 2009-11-12 US claimed
WO-2008093996-A1 METHOD FOR MANUFACTURING TONER LG CHEM, LTD. (KR) 2008-08-07 WO claimed
US-20080071003-A1 Method for Producing Molecularly Imprinted Polymers UNIVERSITY OF DORTMUND INFU (DE) 2008-03-20 US claimed
EP-1781711-A1 METHOD FOR PRODUCING MOLECULARLY IMPRINTED POLYMERS University of Dortmund Infu (DE) 2007-05-09 EP claimed
EP-1136521-B1 Process for preparing an ocular lens material having hydrophilic surface MENICON CO LTD (JP) 2007-02-21 EP claimed
EP-1383828-A4 A METHOD OF TREATING THE SURFACE OF A SUBSTRATE POLYMER USEFUL FOR GRAFT POLYMERIZATION BIO LAYER PTY LTD (AU) 2006-10-04 EP claimed
WO-2006004536-A1 METHOD FOR PRODUCING MOLECULARLY IMPRINTED POLYMERS UNIVERSITY OF DORTMUND INFU (DE) 2006-01-12 WO claimed
US-6858309-B2 Methods of polymerization POLYMERAT PTY. LTD. (AU) 2005-02-22 US claimed
EP-1383828-A1 A METHOD OF TREATING THE SURFACE OF A SUBSTRATE POLYMER USEFUL FOR GRAFT POLYMERIZATION Polymerat Pty Ltd (AU) 2004-01-28 EP claimed
US-20030088028-A1 Methods of polymerization ANTEO TECHNOLOGIES PTY LTD (AU) 2003-05-08 US claimed
US-6533415-B2 Ocular lens material having hydrophilic surface and process for preparing the same MENICON CO., LTD. (JP) 2003-03-18 US claimed
WO-2002079305-A1 A METHOD OF TREATING THE SURFACE OF A SUBSTRATE POLYMER USEFUL FOR GRAFT POLYMERIZATION POLYMERAT PTY LTD (AU) 2002-10-10 WO claimed
US-20010050749-A1 Ocular lens material having hydrophilic surface and process for preparing the same MENICON CO., LTD. (JP) 2001-12-13 US claimed
EP-1136521-A2 Ocular lens material having hydrophilic surface and process for preparing the same Menicon Co., Ltd. (JP) 2001-09-26 EP claimed
US-12624196-B2 Rubber composition, vulcanized object obtained from said rubber composition, and vulcanized molded object obtained from said rubber composition DENKA COMPANY LIMITED (JP) 2026-05-12 US disclosed
EP-0910587-A1 POLYMERIZATION WITH LIVING CHARACTERISTICS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1999-04-28 EP disclosed
WO-1998001478-A1 POLYMERIZATION WITH LIVING CHARACTERISTICS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1998-01-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12624196-B2 Rubber composition, vulcanized object obtained from said rubber composition, and vulcanized molded object obtained from said rubber composition ALG3, VCL, DNMT1 HCAR2 2308/4885ALDH1A1 2251/4885CYP3A4 2969/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.