Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13322023 | 0.93 | LMNA (0.46) | LMNAHSD17B10CYP3A4ALDH1A1CA2 | |
| SCHEMBL1356320 | 0.88 | ALDH1A1 (0.50) | LMNAHSD17B10CYP3A4ALDH1A1CA2 | |
| SCHEMBL1357035 | 0.88 | ALDH1A1 (0.50) | LMNAHSD17B10CYP3A4ALDH1A1CA2 | |
| SCHEMBL13080938 | 0.88 | HRH3 (0.45) | CYP3A4ALDH1A1CA2MAPTHRH3 | |
| SCHEMBL13354068 | 0.87 | LMNA (0.42) | LMNAHSD17B10CYP3A4ALDH1A1CA2 | |
| SCHEMBL20357876 | 0.83 | CYP3A4 (0.47) | LMNAHSD17B10CYP3A4ALDH1A1CA2 | |
| SCHEMBL1822785 | 0.82 | TDP1 (0.56) | LMNAHSD17B10CYP3A4ALDH1A1CA2 | |
| SCHEMBL762244 | 0.82 | CYP3A4 (0.45) | LMNAHSD17B10CYP3A4ALDH1A1CA2 | |
| SCHEMBL13053119 | 0.82 | ALDH1A1 (0.45) | LMNAHSD17B10CYP3A4ALDH1A1CA2 | |
| SCHEMBL11236714 | 0.81 | LMNA (0.38) | LMNAHSD17B10CYP3A4ALDH1A1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2224790-B1 | Light emitting element and azole compound | UDC IRELAND LTD (IE) | 2013-01-02 | — | — | EP | disclosed |