Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14405370 | 1.00 | LMNA (0.42) | LMNAL3MBTL1TDP1THRBPDE4A | |
| SCHEMBL14406486 | 1.00 | LMNA (0.42) | LMNAL3MBTL1TDP1THRBPDE4A | |
| SCHEMBL3462903 | 1.00 | LMNA (0.42) | LMNAL3MBTL1TDP1THRBPDE4A | |
| SCHEMBL14542711 | 1.00 | LMNA (0.42) | LMNAL3MBTL1TDP1THRBPDE4A | |
| SCHEMBL8006354 | 0.97 | TDP1 (0.45) | LMNAL3MBTL1TDP1THRBPDE4A | |
| SCHEMBL22345908 | 0.97 | TDP1 (0.45) | LMNAL3MBTL1TDP1THRBPDE4A | |
| SCHEMBL3458843 | 0.90 | THRB (0.40) | LMNAL3MBTL1TDP1THRBPDE4A | |
| SCHEMBL7120177 | 0.87 | TDP1 (0.53) | LMNAL3MBTL1TDP1THRBPDE4A | |
| SCHEMBL15484277 | 0.83 | THRB (0.44) | LMNAL3MBTL1TDP1THRBALDH1A1 | |
| SCHEMBL12483699 | 0.81 | LMNA (0.69) | LMNAL3MBTL1TDP1THRBPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8344133-B2 | Neoglycorandomization and digitoxin analogs | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2013-01-01 | — | — | US | disclosed |