SCHEMBL14407751

SCHEMBL14407751

CC(=O)Oc1ccc(OC(=O)c2ccc(OC(=O)c3ccc(C)cc3)cc2)cc1

nearest known ligand 0.77

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.77
PRSS1 P07477 1/20 0.61
ACR P10323 1/20 0.61
ELANE P08246 1/20 0.56
HSD17B10 Q99714 2/20 0.55
KMT2A Q03164 7/20 0.54
MEN1 O00255 2/20 0.54
TDP1 Q9NUW8 2/20 0.53
ALDH1A1 P00352 3/20 0.51
CYP1A2 P05177 1/20 0.51
CYP2C9 P11712 1/20 0.51
GBA1 P04062 1/20 0.51
NPC1 O15118 1/20 0.50
RAB9A P51151 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
RXFP1 Q9HBX9 1/20 0.50
MAPT P10636 1/20 0.50
GAA P10253 1/20 0.49
HPGD P15428 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11583538 1.00 LMNA (0.77) LMNAPRSS1ACRELANEHSD17B10
SCHEMBL14484261 1.00 LMNA (0.77) LMNAPRSS1ACRELANEHSD17B10
SCHEMBL14370322 1.00 LMNA (0.77) LMNAPRSS1ACRELANEHSD17B10
SCHEMBL9760675 0.92 ELANE (0.64) LMNAPRSS1ACRELANEHSD17B10
SCHEMBL2741098 0.92 PRSS1 (0.69) LMNAPRSS1ACRHSD17B10KMT2A
SCHEMBL8930157 0.92 PRSS1 (0.69) LMNAPRSS1ACRHSD17B10KMT2A
SCHEMBL1101878 0.92 PRSS1 (0.69) LMNAPRSS1ACRHSD17B10KMT2A
SCHEMBL8929987 0.92 PRSS1 (0.69) LMNAPRSS1ACRHSD17B10KMT2A
SCHEMBL9663961 0.92 PRSS1 (0.69) LMNAPRSS1ACRHSD17B10KMT2A
SCHEMBL8850878 0.92 ELANE (0.64) LMNAPRSS1ACRELANEHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9383491-B2 Retardation film, polarizing plate, and liquid crystal display FUJIFILM CORPORATION (JP) 2016-07-05 US disclosed
US-20160131809-A1 PHASE DIFFERENCE FILM, POLARIZATION PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2016-05-12 US disclosed
US-20150029445-A1 RETARDATION FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY FUJIFILM CORPORATION (JP) 2015-01-29 US disclosed
US-7270855-B2 Optical film, method for manufacturing the same, and phase difference film and polarizing plate using the same NITTO DENKO CORPORATION (JP) 2007-09-18 US disclosed
US-7270855-B2 Optical film, method for manufacturing the same, and phase difference film and polarizing plate using the same NITTO DENKO CORPORATION (JP) 2007-09-18 US disclosed