Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TNF | P01375 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | CTSA | P10619 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30540379 | 0.88 | ACHE (0.59) | GAAACHEKMT2ASMN1; SMN2TNF | |
| SCHEMBL5720955 | 0.88 | ACHE (0.59) | GAAACHEKMT2ASMN1; SMN2TNF | |
| SCHEMBL4671897 | 0.88 | ACHE (0.59) | GAAACHEKMT2ASMN1; SMN2TNF | |
| SCHEMBL2991798 | 0.88 | ACHE (0.59) | GAAACHEKMT2ASMN1; SMN2TNF | |
| Hydrochloric Acid SCHEMBL5743213 | 0.86 | ACHE (0.57) | GAAACHEKMT2ASMN1; SMN2TNF | |
| Hydrochloric Acid SCHEMBL5742665 | 0.86 | ACHE (0.57) | GAAACHEKMT2ASMN1; SMN2TNF | |
| Hydrochloric Acid SCHEMBL5905254 | 0.86 | ACHE (0.57) | GAAACHEKMT2ASMN1; SMN2TNF | |
| SCHEMBL10381531 | 0.85 | GAA (0.53) | FFAR1GAAACHEKMT2ASMN1; SMN2 | |
| SCHEMBL11225638 | 0.84 | FFAR1 (0.56) | FFAR1GAAACHESLC6A2SLC6A4 | |
| SCHEMBL23462724 | 0.84 | ALDH1A1 (0.44) | FFAR1ACHESLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7268164-B2 | Anti-epileptogenic agents | QUEENS UNIVERSITY AT KINGSTON (CA) | 2007-09-11 | — | — | US | disclosed |
| US-7268164-B2 | Anti-epileptogenic agents | QUEENS UNIVERSITY AT KINGSTON (CA) | 2007-09-11 | — | — | US | disclosed |