SCHEMBL5159805

SCHEMBL5159805

CO[C@H]1O[C@H](C)[C@@H](N[C@@H]2C=C(CO)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@H]1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MGAM O43451 8/20 1.00
SI P14410 7/20 1.00
AMY2A P04746 8/20 0.68
GAA P10253 4/20 0.67
AMY1A P0DUB6 3/20 0.67
CNR1 P21554 1/20 0.67
PTGS1 P23219 1/20 0.67
PDE4A P27815 1/20 0.67
PDE3A Q14432 1/20 0.67
MGAM2 Q2M2H8 1/20 0.67
ALDH1A1 P00352 1/20 0.67
GLA P06280 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14408601 1.00 MGAM (1.00) MGAMSIAMY2AGAAAMY1A
SCHEMBL14408602 1.00 MGAM (1.00) MGAMSIAMY2AGAAAMY1A
SCHEMBL30937785 1.00 MGAM (1.00) MGAMSIAMY2AGAAAMY1A
SCHEMBL14408731 1.00 MGAM (1.00) MGAMSIAMY2AGAAAMY1A
SCHEMBL14408476 1.00 MGAM (1.00) MGAMSIAMY2AGAAAMY1A
SCHEMBL5158956 1.00 MGAM (1.00) MGAMSIAMY2AGAAAMY1A
SCHEMBL14408605 1.00 MGAM (1.00) MGAMSIAMY2AGAAAMY1A
SCHEMBL14408698 1.00 MGAM (1.00) MGAMSIAMY2AGAAAMY1A
SCHEMBL14408606 1.00 MGAM (1.00) MGAMSIAMY2AGAAAMY1A
SCHEMBL14416167 0.89 AMY2A (0.87) MGAMSIAMY2AGAAAMY1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220144747-A1 SHIKIMATE ANALOGUES AND METHODS OF USE THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA 2022-05-12 US claimed
US-12599562-B2 Nanocrystal microparticles of poorly soluble drugs and methods of production and use thereof THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) 2026-04-14 US disclosed
EP-3880688-B1 OLIGOSACCHARIDE PREPARATIONS AND COMPOSITIONS DSM IP ASSETS BV (NL) 2025-09-17 EP disclosed
EP-4613755-A1 OLIGOSACCHARIDE PREPARATIONS AND COMPOSITIONS DSM IP Assets B.V. (NL) 2025-09-10 EP disclosed
US-12383570-B2 Methods of selectively modulating gastrointestinal microbial growth DSM IP ASSETS B.V. (NL) 2025-08-12 US disclosed
US-12377113-B2 Glycan therapeutic compositions and related methods thereof DSM NUTRITIONAL PRODUCTS, LLC (US) 2025-08-05 US disclosed
US-20250212913-A1 METHODS OF MODULATING GASTROINTESTINAL METABOLITES DSM IP ASSETS BV (NL) 2025-07-03 US disclosed
US-20250185694-A1 METHODS OF MODULATING GASTROINTESTINAL METABOLITES DSM IP ASSETS BV (NL) 2025-06-12 US disclosed
US-20250185695-A1 METHODS OF MODULATING GASTROINTESTINAL METABOLITES DSM IP ASSETS BV (NL) 2025-06-12 US disclosed
US-20250185692-A1 METHODS OF MODULATING GASTROINTESTINAL METABOLITES DSM IP ASSETS BV (NL) 2025-06-12 US disclosed
CN-107427528-B Glycan therapeutics and methods related thereto 卡莱多生物科技有限公司 2022-09-23 CN disclosed
EP-4045520-A1 METHODS FOR THE IMPROVED FORMATION OF ACARBOSE Bayer Aktiengesellschaft (DE) 2022-08-24 EP disclosed
US-20220233577-A1 GLYCAN PREPARATIONS AND METHODS OF USE FOR HYPERAMMONEMIA KALEIDO BIOSCIENCES, INC. 2022-07-28 US disclosed
US-11369592-B2 Treatment of human coronavirus infections using alpha-glucosidase glycoprotein processing inhibitors FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2022-06-28 US disclosed
CN-114555811-A Method for improving acarbose formation 拜耳公司 2022-05-27 CN disclosed
US-20220144747-A1 SHIKIMATE ANALOGUES AND METHODS OF USE THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA 2022-05-12 US disclosed
US-20220125074-A1 METHODS OF MODULATING GASTROINTESTINAL METABOLITES DSM IP ASSETS B.V. (NL) 2022-04-28 US disclosed
US-7271158-B2 Treatment of rumen acidosis with α-amylase inhibitors PFIZER INC. (US) 2007-09-18 US disclosed
EP-1745790-A2 Treatment of rumen acidosis with alpha-amylase inhibitors Pfizer Limited (GB) 2007-01-24 EP disclosed
US-20050233983-A1 Treatment of rumen acidosis with alpha-amylase inhibitors BANKS BERNARD J 2005-10-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11369592-B2 Treatment of human coronavirus infections using alpha-glucosidase glycoprotein processing inhibitors ACE2, ACE, GAA MGAM 12/4885SI 27/4885AMY2A 94/4885
US-12599562-B2 Nanocrystal microparticles of poorly soluble drugs and methods of production and use thereof CDK4, CDK5, CDK6 MGAM 3058/4885SI 1182/4885AMY2A 4239/4885
US-20050233983-A1 Treatment of rumen acidosis with alpha-amylase inhibitors SI, GANAB, AMY1A MGAM 7/4885SI 1/4885AMY2A 13/4885
US-20220144747-A1 SHIKIMATE ANALOGUES AND METHODS OF USE GRIK5, GRIK1, GRIK3 MGAM 2059/4885SI 67/4885AMY2A 2355/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.