Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.58 |
| ▸ | USP14 | P54578 | 14/20 | 0.57 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2983398 | 0.90 | RORC (0.54) | RORCUSP14HDAC6CNR2 | |
| SCHEMBL2978432 | 0.80 | RORC (0.56) | RORCUSP14HDAC6CNR2 | |
| SCHEMBL19298011 | 0.79 | USP14 (0.70) | RORCUSP14 | |
| SCHEMBL18235058 | 0.79 | USP14 (0.70) | RORCUSP14 | |
| SCHEMBL18235061 | 0.76 | USP14 (0.66) | RORCUSP14 | |
| SCHEMBL13740012 | 0.73 | USP14 (1.00) | USP14 | |
| SCHEMBL2984681 | 0.73 | RORC (0.51) | RORCUSP14HDAC6 | |
| SCHEMBL1744667 | 0.72 | SRD5A2 (0.57) | — | |
| SCHEMBL2980941 | 0.72 | SMN1; SMN2 (0.54) | RORC | |
| SCHEMBL13741172 | 0.72 | USP14 (1.00) | USP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1837329-A1 | NOVEL HETEROARYL DERIVATIVE | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2007-09-26 | — | — | EP | disclosed |