Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 5/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | SRC | P12931 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL154140 | 0.78 | NTRK1 (0.49) | IDO1NTRK1MAPTLMNAHTT | |
| SCHEMBL29930277 | 0.78 | NTRK1 (0.49) | IDO1NTRK1MAPTLMNAHTT | |
| SCHEMBL154801 | 0.77 | LMNA (0.43) | IDO1NTRK1MAPTKDM4EHPGD | |
| SCHEMBL152144 | 0.75 | IDO1 (0.49) | IDO1NTRK1MAPTKDM4EHPGD | |
| SCHEMBL144098 | 0.75 | NTRK1 (0.45) | IDO1NTRK1MAPTLMNAHTT | |
| SCHEMBL142571 | 0.72 | NTRK1 (0.45) | IDO1NTRK1MAPTLMNAHTT | |
| SCHEMBL143247 | 0.72 | IDO1 (0.45) | IDO1NTRK1MAPTLMNAHTT | |
| SCHEMBL142563 | 0.71 | NTRK1 (0.48) | IDO1NTRK1MAPTKDM4EHSD17B10 | |
| SCHEMBL11926706 | 0.69 | MYC (0.66) | TSHRNR4A2MAPTKDM4EHSD17B10 | |
| SCHEMBL2555522 | 0.69 | ALDH1A1 (0.57) | TSHRNR4A2MAPTKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8940909-B2 | Indicator platform | BIOSYNTH AG (CH) | 2015-01-27 | — | — | US | disclosed |
| US-8940909-B2 | Indicator platform | BIOSYNTH AG (CH) | 2015-01-27 | — | — | US | disclosed |
| EP-2427431-B1 | NOVEL INDICATOR PLATFORM | BIOSYNTH AG (CH) | 2013-05-01 | — | — | EP | disclosed |
| US-20120058503-A1 | Novel Indicator Platform | BIOSYNTH AG (CH) | 2012-03-08 | — | — | US | disclosed |
| WO-2010128120-A1 | NOVEL INDICATOR PLATFORM | BIOSYNTH AG (CH) | 2010-11-11 | — | — | WO | disclosed |