Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 2/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 2/20 | 0.49 |
| ▸ | BLM | P54132 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | TOP2A | P11388 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | MTOR | P42345 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5424441 | 0.99 | NQO1 (0.51) | NQO1CYP19A1SMN1; SMN2HIF1AMEN1 | |
| SCHEMBL14466495 | 0.93 | NQO1 (0.47) | NQO1CYP19A1SMN1; SMN2HIF1AMEN1 | |
| SCHEMBL13800043 | 0.92 | NPSR1 (0.42) | NQO1CYP19A1SMN1; SMN2HIF1AMEN1 | |
| SCHEMBL30513721 | 0.89 | CYP19A1 (0.62) | NQO1CYP19A1SMN1; SMN2HIF1AMEN1 | |
| SCHEMBL29527683 | 0.89 | CYP19A1 (0.62) | NQO1CYP19A1SMN1; SMN2HIF1AMEN1 | |
| SCHEMBL3148984 | 0.89 | CYP19A1 (0.62) | NQO1CYP19A1SMN1; SMN2HIF1AMEN1 | |
| SCHEMBL11522777 | 0.89 | CYP19A1 (0.62) | NQO1CYP19A1SMN1; SMN2HIF1AMEN1 | |
| SCHEMBL11277491 | 0.89 | CYP19A1 (0.62) | NQO1CYP19A1SMN1; SMN2HIF1AMEN1 | |
| SCHEMBL3418071 | 0.89 | CYP19A1 (0.62) | NQO1CYP19A1SMN1; SMN2HIF1AMEN1 | |
| SCHEMBL1202596 | 0.89 | CYP19A1 (0.62) | NQO1CYP19A1SMN1; SMN2HIF1AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070208085-A1 | Potent cytotoxicity and inhibition of pan-cell cycle progression by an alkylating anthraquinone | SOMANTA LIMITED (GB) | 2007-09-06 | — | — | US | disclosed |
| US-20070208085-A1 | Potent cytotoxicity and inhibition of pan-cell cycle progression by an alkylating anthraquinone | SOMANTA LIMITED (GB) | 2007-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070208085-A1 | Potent cytotoxicity and inhibition of pan-cell cycle progression by an alkylating anthraquinone | BOD1L1, CDC25C, CCNI | NQO1 465/4885CYP19A1 2347/4885SMN1; SMN2 4219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.