Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | HRH1 | P35367 | 2/20 | 0.45 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | BCL2 | P10415 | 2/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13681433 | 0.85 | HTR2A (0.47) | HTR2AHRH1BCL2L1MAOAMAOB | |
| SCHEMBL13681378 | 0.83 | HTR2A (0.45) | HTR2AHRH1BCL2L1MAOAMAOB | |
| SCHEMBL13681434 | 0.81 | HTR2A (0.42) | HTR2AHRH1BCL2L1MAOAMAOB | |
| SCHEMBL10080801 | 0.79 | MAOA (0.41) | HTR2AHRH1BCL2L1MAOAMAOB | |
| SCHEMBL2953412 | 0.77 | MTNR1A (0.46) | HTR2AHRH1BCL2L1MAOAMAOB | |
| SCHEMBL2953408 | 0.77 | MTNR1A (0.46) | HTR2AHRH1BCL2L1MAOAMAOB | |
| SCHEMBL13503887 | 0.76 | BCL2L1 (0.48) | HTR2AHRH1BCL2L1MAOAMAOB | |
| SCHEMBL24697532 | 0.74 | BCL2L1 (0.47) | HTR2AHRH1BCL2L1MAOAMAOB | |
| SCHEMBL13503923 | 0.74 | BCL2L1 (0.47) | HTR2AHRH1BCL2L1MAOAMAOB | |
| SCHEMBL24774558 | 0.72 | BCL2L1 (0.46) | HTR2AHRH1BCL2L1MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1487811-B1 | N-SULFONYLUREA APOPTOSIS PROMOTERS | ABBOTT LAB (US) | 2007-09-05 | — | — | EP | disclosed |