Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 12/20 | 0.50 |
| ▸ | CPB1 | P15086 | 5/20 | 0.40 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.39 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27803087 | 0.86 | CPB2 (0.53) | CPB2CPB1LPAR1KDM4EALDH1A1 | |
| SCHEMBL27803207 | 0.83 | CPB2 (0.55) | CPB2CPB1LPAR1ALDH1A1 | |
| SCHEMBL7278477 | 0.82 | CPB2 (0.48) | CPB2CPB1MAP3K5CYP2E1CYP3A4 | |
| SCHEMBL27803083 | 0.80 | CPB2 (0.54) | CPB2CPB1ALDH1A1 | |
| SCHEMBL27781569 | 0.80 | CPB2 (0.54) | CPB2CPB1ALDH1A1 | |
| SCHEMBL7256341 | 0.78 | CPB2 (0.50) | CPB2CPB1LPAR1 | |
| SCHEMBL14481389 | 0.78 | CPB2 (0.44) | CPB2CPB1LPAR1 | |
| SCHEMBL876467 | 0.77 | CYP2C9 (0.50) | CPB2CYP2C9CYP2C19KDM4EALDH1A1 | |
| SCHEMBL27340963 | 0.77 | CYP2C9 (0.50) | CPB2CYP2C9CYP2C19KDM4EALDH1A1 | |
| SCHEMBL4852398 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011028112-A1 | IMIDAZOLE-4-CARBOXYLIC ACID FOR USE IN TREATING A DISEASE RELATED TO EXTRACELLULAR REACTIVE OXYGEN SPECIES | VALLETTA HEALTH B.V. (NL) | 2011-03-10 | — | — | WO | disclosed |