Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 7/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SCD | O00767 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14960376 | 0.77 | ALDH1A1 (0.53) | ALDH1A1POLBGAACHRM2LMNA | |
| SCHEMBL13009140 | 0.76 | ALDH1A1 (0.43) | ALDH1A1POLBGAAL3MBTL1MEN1 | |
| SCHEMBL14412177 | 0.75 | NPC1 (0.50) | ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL14412392 | 0.74 | ALDH1A1 (0.41) | ALDH1A1POLBGAAPDK2 | |
| SCHEMBL14412418 | 0.73 | ALDH1A1 (0.50) | ALDH1A1POLBGAAS1PR1TSHR | |
| SCHEMBL14412447 | 0.73 | TRPV1 (0.43) | ALDH1A1POLBGAAL3MBTL1PDK2 | |
| SCHEMBL14412199 | 0.72 | ALDH1A1 (0.51) | ALDH1A1GAATSHRMEN1KMT2A | |
| SCHEMBL2057993 | 0.71 | ALDH1A1 (0.57) | ALDH1A1POLBGAALMNAUSP2 | |
| SCHEMBL1594998 | 0.70 | ALDH1A1 (0.63) | ALDH1A1POLBGAAL3MBTL1MEN1 | |
| SCHEMBL14412457 | 0.70 | ALDH1A1 (0.46) | ALDH1A1POLBGAAL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007100851-A1 | THERAPEUTIC COMPOUNDS | HELICON THERAPEUTICS, INC. (US) | 2007-09-07 | — | — | WO | disclosed |