Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 5/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14413648 | 0.90 | EPHX2 (0.64) | EPHX2ALDH1A1MAPTRAB9AKMT2A | |
| SCHEMBL13873300 | 0.87 | EPHX2 (1.00) | EPHX2ALDH1A1MAPTTDP1KMT2A | |
| SCHEMBL11718912 | 0.84 | EPHX2 (0.67) | EPHX2ALDH1A1MAPTTDP1KMT2A | |
| SCHEMBL11720518 | 0.79 | EPHX2 (0.61) | EPHX2ALDH1A1MAPTRAB9ATDP1 | |
| SCHEMBL11719448 | 0.79 | KMT2A (0.70) | EPHX2ALDH1A1MAPTRAB9AKMT2A | |
| SCHEMBL13873299 | 0.78 | EPHX2 (0.83) | EPHX2ALDH1A1TDP1KMT2ANAMPT | |
| SCHEMBL13873295 | 0.76 | EPHX2 (0.81) | EPHX2ALDH1A1MAPTTDP1KMT2A | |
| SCHEMBL14413644 | 0.75 | EPHX2 (0.75) | EPHX2MAPTKMT2AMEN1THRB | |
| SCHEMBL14413342 | 0.74 | SMN1; SMN2 (0.72) | EPHX2ALDH1A1MAPTRAB9AKMT2A | |
| SCHEMBL10524953 | 0.72 | EPHX2 (0.61) | EPHX2ALDH1A1MAPTRAB9ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007106705-A1 | SOLUBLE EPOXIDE HYDROLASE INHIBITORS AND METHODS OF USING SAME | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-09-20 | — | — | WO | disclosed |