Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 5/20 | 0.75 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | FAAH | O00519 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14413584 | 0.90 | EPHX2 (0.65) | EPHX2ALOX5SMN1; SMN2MEN1KMT2A | |
| SCHEMBL13873298 | 0.86 | EPHX2 (1.00) | EPHX2ALOX5CYP2C9CYP2C19POLB | |
| SCHEMBL14413342 | 0.80 | SMN1; SMN2 (0.72) | EPHX2SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL13623458 | 0.77 | EPHX2 (0.84) | EPHX2ALOX5CYP2C9CYP2C19POLB | |
| SCHEMBL14413643 | 0.75 | EPHX2 (0.77) | EPHX2SMN1; SMN2MEN1KMT2ATHRB | |
| SCHEMBL13623462 | 0.73 | EPHX2 (0.77) | EPHX2ALOX5CYP2C9CYP2C19POLB | |
| SCHEMBL14413645 | 0.72 | KDM4E (0.68) | EPHX2SMN1; SMN2KMT2AMAPT | |
| SCHEMBL11981665 | 0.72 | KMT2A (0.61) | EPHX2ALOX5SMN1; SMN2KMT2AMAPT | |
| SCHEMBL13873288 | 0.72 | EPHX2 (1.00) | EPHX2SMN1; SMN2CYP2C9CYP2C19POLB | |
| SCHEMBL13873284 | 0.71 | SMN1; SMN2 (0.74) | EPHX2SMN1; SMN2MEN1KMT2AFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007106705-A1 | SOLUBLE EPOXIDE HYDROLASE INHIBITORS AND METHODS OF USING SAME | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-09-20 | — | — | WO | disclosed |