SCHEMBL14415151

SCHEMBL14415151

CC(=O)Nc1c(Br)cc([N+](=O)[O-])cc1Br

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.50
MAPT P10636 4/20 0.47
LMNA P02545 4/20 0.46
KMT2A Q03164 5/20 0.45
MEN1 O00255 3/20 0.45
HSP90AA1 P07900 1/20 0.45
GAA P10253 2/20 0.45
CYP1A2 P05177 1/20 0.45
ALDH1A1 P00352 3/20 0.44
CYP3A4 P08684 1/20 0.44
KDM4E B2RXH2 1/20 0.44
POLB P06746 1/20 0.44
HTT P42858 1/20 0.42
DYRK1A Q13627 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8331035 0.90 SMN1; SMN2 (0.45) SMN1; SMN2MAPTLMNAKMT2AMEN1
SCHEMBL8334546 0.86 KMT2A (0.52) SMN1; SMN2MAPTLMNAKMT2AMEN1
SCHEMBL11855622 0.85 SMN1; SMN2 (0.41) SMN1; SMN2MAPTLMNAKMT2AMEN1
SCHEMBL25422900 0.84 KMT2A (0.44) SMN1; SMN2MAPTLMNAKMT2AMEN1
SCHEMBL28346418 0.83 MAPT (0.44) SMN1; SMN2MAPTLMNAKMT2AMEN1
SCHEMBL18946229 0.81 MEN1 (0.56) MAPTKMT2AMEN1HSP90AA1ALDH1A1
SCHEMBL3597390 0.80 SMN1; SMN2 (0.51) SMN1; SMN2MAPTLMNAKMT2AMEN1
SCHEMBL10882422 0.80 SMN1; SMN2 (0.51) SMN1; SMN2MAPTLMNAKMT2AMEN1
SCHEMBL8466527 0.79 SMN1; SMN2 (0.50) SMN1; SMN2MAPTLMNAKMT2AMEN1
SCHEMBL7520916 0.79 KMT2A (0.55) SMN1; SMN2MAPTLMNAKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240309038-A1 NOVEL GALACTOSIDE INHIBITOR OF GALECTINS GALECTO BIOTECH AB (DK) 2024-09-19 US disclosed
CN-117043156-A Novel galectin inhibitors of galectins 格莱克特生物技术公司 2023-11-10 CN disclosed
EP-4267568-A1 NOVEL GALACTOSIDE INHIBITOR OF GALECTINS Galecto Biotech AB (DK) 2023-11-01 EP disclosed
WO-2023118267-A1 NOVEL GALACTOSIDE INHIBITOR OF GALECTINS GALECTO BIOTECH AB (DK) 2023-06-29 WO disclosed
WO-2023118267-A1 NOVEL GALACTOSIDE INHIBITOR OF GALECTINS GALECTO BIOTECH AB (DK) 2023-06-29 WO disclosed
WO-2022144274-A1 NOVEL GALACTOSIDE INHIBITOR OF GALECTINS GALECTO BIOTECH AB (DK) 2022-07-07 WO disclosed
US-7270857-B2 Liquid crystal composition and liquid crystal element FUJIFILM CORPORATION (JP) 2007-09-18 US disclosed
US-7270857-B2 Liquid crystal composition and liquid crystal element FUJIFILM CORPORATION (JP) 2007-09-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240309038-A1 NOVEL GALACTOSIDE INHIBITOR OF GALECTINS LGALS3, LGALS1, LGALS3BP SMN1; SMN2 3245/4885MAPT 2329/4885LMNA 815/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.