SCHEMBL14415596

SCHEMBL14415596

CNC[C@H](C)C(c1cccc(F)c1)c1cccc(F)c1

nearest known ligand 0.65

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 15/20 0.48
SLC6A4 P31645 15/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14415578 0.83 LMNA (0.43) SLC6A2SLC6A4
SCHEMBL14415574 0.83 LMNA (0.43) SLC6A2SLC6A4
SCHEMBL6001269 0.79 SLC6A2 (0.46) SLC6A2SLC6A4
Ammonia Solution, Strong SCHEMBL5999554 0.79 AOC3 (0.41) SLC6A2SLC6A4
SCHEMBL14415571 0.79 SLC6A2 (0.46) SLC6A2SLC6A4
SCHEMBL14415572 0.79 SLC6A2 (0.46) SLC6A2SLC6A4
SCHEMBL13272288 0.79 SLC6A4 (0.50) SLC6A2SLC6A4
SCHEMBL16552595 0.78 SLC6A2 (0.64) SLC6A2SLC6A4
SCHEMBL2291430 0.77 ADRB1 (0.67) SLC6A2SLC6A4
SCHEMBL2292241 0.77 ADRB1 (0.67) SLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7268166-B2 Compounds active at a novel site on receptor-operated calcium channels useful for treatment of neurological disorders and diseases NPS PHARMACEUTICALS, INC. (US) 2007-09-11 US disclosed
US-7268166-B2 Compounds active at a novel site on receptor-operated calcium channels useful for treatment of neurological disorders and diseases NPS PHARMACEUTICALS, INC. (US) 2007-09-11 US disclosed