Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14415750 | 0.84 | MAP3K14 (0.31) | — | |
| SCHEMBL5045280 | 0.82 | CRHR1 (0.33) | CRHR1 | |
| SCHEMBL5046719 | 0.74 | CRHR1 (0.33) | CRHR1 | |
| SCHEMBL5048598 | 0.73 | CRHR1 (0.33) | CRHR1 | |
| SCHEMBL14415754 | 0.71 | CRHR1 (0.30) | CRHR1 | |
| SCHEMBL5394886 | 0.69 | CRHR1 (0.54) | CRHR1 | |
| SCHEMBL14049595 | 0.64 | RXRA (0.32) | CRHR1 | |
| Trifluoroacetic Acid SCHEMBL5774973 | 0.64 | SLC2A1 (0.32) | CRHR1 | |
| SCHEMBL5039764 | 0.64 | CRHR1 (0.32) | CRHR1 | |
| SCHEMBL5039393 | 0.64 | CRHR1 (0.32) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7268146-B2 | Ring fused pyrazole derivatives as CRF antagonists | PALO ALTO LLC (US) | 2007-09-11 | — | — | US | disclosed |
| US-7268146-B2 | Ring fused pyrazole derivatives as CRF antagonists | PALO ALTO LLC (US) | 2007-09-11 | — | — | US | disclosed |