Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25455194 | 0.81 | CHRM4 (0.37) | NAMPTCHRM5CHRM4CHRM1CYP2C9 | |
| SCHEMBL18995940 | 0.79 | HRH4 (0.38) | NAMPTCHRM5CHRM4CHRM1CYP2C9 | |
| SCHEMBL16812917 | 0.77 | MEN1 (0.40) | NAMPTCHRM5CHRM4CHRM1CYP2C9 | |
| SCHEMBL4101630 | 0.77 | CHRM5 (0.37) | CHRM5CHRM4CHRM1CYP2C9CHRM3 | |
| SCHEMBL10425365 | 0.75 | CHRM5 (0.43) | CHRM5CHRM4CHRM1CYP2C9CHRM3 | |
| SCHEMBL16373637 | 0.75 | CHRM5 (0.36) | NAMPTCHRM5CHRM4CHRM1CYP2C9 | |
| SCHEMBL14415982 | 0.74 | CHRM5 (0.40) | NAMPTCHRM5CHRM4CHRM1CYP2C9 | |
| SCHEMBL14415976 | 0.73 | CYP3A4 (0.52) | CHRM2MEN1CYP3A4CYP2C19KMT2A | |
| SCHEMBL14003756 | 0.72 | HRH3 (0.36) | CHRM5CHRM4CHRM1CYP2C9CHRM3 | |
| SCHEMBL16812145 | 0.72 | HRH4 (0.38) | NAMPTCHRM5CHRM4CHRM1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070213340-A1 | Farnesyl protein transferase inhibitors | SCHERING CORPORATION | 2007-09-13 | — | — | US | disclosed |
| US-20070213340-A1 | Farnesyl protein transferase inhibitors | SCHERING CORPORATION | 2007-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070213340-A1 | Farnesyl protein transferase inhibitors | FNTB, FNTA, FDPS | NAMPT 899/4885CHRM5 4138/4885CHRM4 3603/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.