Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MPO | P05164 | 1/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14416067 | 0.91 | SIGMAR1 (0.49) | CYP3A4CYP2D6CYP2C19GAAMAPT | |
| SCHEMBL6968640 | 0.75 | CYP1A2 (0.50) | CYP3A4CYP2D6CYP2C19GAAMAPT | |
| SCHEMBL4901285 | 0.74 | FNTA (0.56) | — | |
| SCHEMBL14416030 | 0.74 | MAOA (0.46) | MEN1KMT2ATDP1SIGMAR1MAOA | |
| SCHEMBL16812917 | 0.73 | MEN1 (0.40) | CYP3A4CYP2C19MAPTHRH4MEN1 | |
| SCHEMBL14415977 | 0.73 | NAMPT (0.35) | CYP3A4CYP2C19MAPTMEN1KMT2A | |
| SCHEMBL14415978 | 0.73 | HRH4 (0.41) | CYP3A4CYP2C19MAPTHRH4MEN1 | |
| SCHEMBL14416032 | 0.73 | MEN1 (0.47) | GAAMAPTHRH4MEN1KMT2A | |
| SCHEMBL21139472 | 0.72 | NAMPT (0.55) | GAAMAPTMEN1KMT2AEPHX2 | |
| SCHEMBL10425365 | 0.72 | CHRM5 (0.43) | CYP3A4CYP2C19MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070213340-A1 | Farnesyl protein transferase inhibitors | SCHERING CORPORATION | 2007-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070213340-A1 | Farnesyl protein transferase inhibitors | FNTB, FNTA, FDPS | CYP3A4 253/4885CYP2D6 2321/4885CYP2C19 2298/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.