SCHEMBL14416243

CC(=O)OC1C(OC(C)=O)[C@@H](OCc2ccccc2)C(COCc2ccccc2)O[C@@H]1O[C@@H]1C(OCc2ccccc2)[C@@H](OCC2O[C@H](C)C(OCc3ccccc3)[C@@H](O[C@H]3OC(COCc4ccccc4)[C@H](OCc4ccccc4)C(OC(C)=O)C3O[C@H]3OC(COCc4ccccc4)[C@H](OCc4ccccc4)C(OC(C)=O)C3O[C@H]3OC(COCc4ccccc4)[C@H](OCc4ccccc4)C(OC(C)=O)C3OC(C)=O)[C@@H]2OCc2ccccc2)OC(CO[C@H]2OC(CO[C@H]3OC(COCc4ccccc4)[C@@H](OCc4ccccc4)[C@H](OC(C)=O)C3OCc3ccccc3)[C@@H](OCc3ccccc3)[C@H](O)C2OCc2ccccc2)[C@H]1OCc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 18)

	gene	UniProt	supporting neighbours	confidence
▸	GJB2	P29033	3/20	0.47

▸	NT5E	P21589	1/20	0.45

▸	PTPN1	P18031	7/20	0.43

▸	CDC25B	P30305	5/20	0.43

▸	PTPN2	P17706	3/20	0.43

▸	PTPN11	Q06124	3/20	0.43

▸	PTPN6	P29350	2/20	0.42

▸	FGF1	P05230	2/20	0.42

▸	FGF2	P09038	2/20	0.42

▸	VEGFA	P15692	2/20	0.42

▸	HPSE	Q9Y251	2/20	0.42

▸	GJA1	P17302	2/20	0.41

▸	TACR2	P21452	1/20	0.41

▸	SSTR1	P30872	1/20	0.41

▸	SSTR2	P30874	1/20	0.41

▸	SSTR4	P31391	1/20	0.41

▸	SSTR3	P32745	1/20	0.41

▸	SSTR5	P35346	1/20	0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL14416246	0.96	NT5E (0.49)	GJB2NT5EPTPN1CDC25BPTPN2
SCHEMBL14413407	0.95	NT5E (0.48)	NT5EPTPN1CDC25BPTPN2PTPN11
SCHEMBL14413406	0.95	NT5E (0.47)	GJB2NT5EPTPN1CDC25BPTPN2
SCHEMBL14416240	0.89	NT5E (0.47)	GJB2NT5EPTPN1CDC25BPTPN2
SCHEMBL14413429	0.89	NT5E (0.47)	GJB2NT5EPTPN1CDC25BPTPN2
SCHEMBL14416242	0.88	NT5E (0.51)	GJB2NT5EPTPN1CDC25BPTPN2
SCHEMBL14413403	0.88	NT5E (0.51)	GJB2NT5EPTPN1CDC25BPTPN2
SCHEMBL13129822	0.86	NT5E (0.52)	GJB2NT5EPTPN1CDC25BPTPN2
SCHEMBL13129931	0.86	NT5E (0.47)	GJB2NT5EPTPN1CDC25BPTPN2
SCHEMBL14413419	0.85	NT5E (0.47)	GJB2NT5EPTPN1CDC25BPTPN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20070213278-A1	Arrays with cleavable linkers	SCRIPPS RESEARCH INSTITUTE, THE	2007-09-13	—	—	US	disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

Patent	Title	Text reads most about	Predicted target · text-rank
US-20070213278-A1	Arrays with cleavable linkers	ENGASE, ADAM33, SIGLEC7	GJB2 2662/4885NT5E 295/4885PTPN1 3515/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.