Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.47 |
| ▸ | FGF1 | P05230 | 2/20 | 0.46 |
| ▸ | FGF2 | P09038 | 2/20 | 0.46 |
| ▸ | VEGFA | P15692 | 2/20 | 0.46 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 8/20 | 0.45 |
| ▸ | CDC25B | P30305 | 6/20 | 0.45 |
| ▸ | PTPN2 | P17706 | 4/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.44 |
| ▸ | PTPN6 | P29350 | 3/20 | 0.43 |
| ▸ | GJB2 | P29033 | 2/20 | 0.43 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.42 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.42 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.42 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.42 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TACR2 | P21452 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14416246 | 0.99 | NT5E (0.49) | NT5EFGF1FGF2VEGFAHPSE | |
| SCHEMBL14413407 | 0.98 | NT5E (0.48) | NT5EFGF1FGF2VEGFAHPSE | |
| SCHEMBL14416243 | 0.95 | GJB2 (0.47) | NT5EFGF1FGF2VEGFAHPSE | |
| SCHEMBL14413429 | 0.94 | NT5E (0.47) | NT5EFGF1FGF2VEGFAHPSE | |
| SCHEMBL14416240 | 0.94 | NT5E (0.47) | NT5EFGF1FGF2VEGFAHPSE | |
| SCHEMBL14416242 | 0.93 | NT5E (0.51) | NT5EFGF1FGF2VEGFAHPSE | |
| SCHEMBL14413403 | 0.93 | NT5E (0.51) | NT5EFGF1FGF2VEGFAHPSE | |
| SCHEMBL14413419 | 0.90 | NT5E (0.47) | NT5EFGF1FGF2VEGFAHPSE | |
| SCHEMBL13129822 | 0.89 | NT5E (0.52) | NT5EFGF1FGF2VEGFAHPSE | |
| SCHEMBL15617817 | 0.88 | CYP2D6 (0.51) | CYP2D6ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070213278-A1 | Arrays with cleavable linkers | SCRIPPS RESEARCH INSTITUTE, THE | 2007-09-13 | — | — | US | disclosed |
| US-20070213297-A1 | Arrays with cleavable linkers | SCRIPPS RESEARCH INSTITUTE, THE | 2007-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070213278-A1 | Arrays with cleavable linkers | ENGASE, ADAM33, SIGLEC7 | NT5E 295/4885FGF1 2838/4885FGF2 1917/4885 |
| US-20070213297-A1 | Arrays with cleavable linkers | ENGASE, ADAM33, SIGLEC7 | NT5E 295/4885FGF1 2838/4885FGF2 1917/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.