SCHEMBL14416244

SCHEMBL14416244

C[C@H]1OC(CO)[C@@H](OCc2ccccc2)[C@H](O[C@H]2OC(COCc3ccccc3)[C@H](OCc3ccccc3)C(OCc3ccccc3)C2OCc2ccccc2)C1OCc1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ PTPN1 P18031 8/20 0.49
▸ CDC25B P30305 6/20 0.49
▸ SSTR1 P30872 1/20 0.49
▸ SSTR2 P30874 1/20 0.49
▸ SSTR4 P31391 1/20 0.49
▸ SSTR3 P32745 1/20 0.49
▸ SSTR5 P35346 1/20 0.49
▸ PTPN2 P17706 3/20 0.49
▸ PTPN11 Q06124 3/20 0.49
▸ GJB2 P29033 2/20 0.48
▸ NT5E P21589 1/20 0.48
▸ PTPN6 P29350 2/20 0.46
▸ SLC6A2 P23975 1/20 0.44
▸ FGF1 P05230 2/20 0.44
▸ FGF2 P09038 2/20 0.44
▸ VEGFA P15692 2/20 0.44
▸ HPSE Q9Y251 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24378519 0.92 SSTR1 (0.54) PTPN1CDC25BSSTR1SSTR2SSTR4
SCHEMBL13608236 0.91 PTPN1 (0.53) PTPN1CDC25BSSTR1SSTR2SSTR4
SCHEMBL14413419 0.90 NT5E (0.47) PTPN1CDC25BSSTR1SSTR2SSTR4
SCHEMBL14413429 0.88 NT5E (0.47) PTPN1CDC25BPTPN2PTPN11GJB2
SCHEMBL14416240 0.88 NT5E (0.47) PTPN1CDC25BPTPN2PTPN11GJB2
SCHEMBL13129789 0.87 GJB2 (0.50) PTPN1CDC25BSSTR1SSTR2SSTR4
SCHEMBL15975388 0.87 GJB2 (0.50) PTPN1CDC25BSSTR1SSTR2SSTR4
SCHEMBL13129826 0.87 GJB2 (0.50) PTPN1CDC25BSSTR1SSTR2SSTR4
SCHEMBL13129876 0.87 GJB2 (0.50) PTPN1CDC25BSSTR1SSTR2SSTR4
SCHEMBL13129827 0.87 GJB2 (0.50) PTPN1CDC25BSSTR1SSTR2SSTR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070213278-A1 Arrays with cleavable linkers SCRIPPS RESEARCH INSTITUTE, THE 2007-09-13 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070213278-A1 Arrays with cleavable linkers ENGASE, ADAM33, SIGLEC7 PTPN1 3515/4885CDC25B 2026/4885SSTR1 2081/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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