Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14417720 | 0.79 | ALDH1A1 (0.66) | ALDH1A1HPGDKDM4EKMT2AF2 | |
| SCHEMBL14417719 | 0.76 | ALDH1A1 (0.66) | ALDH1A1HPGDKDM4EKMT2AF2 | |
| SCHEMBL7191472 | 0.75 | IKBKB (0.42) | ALDH1A1KDM4EKMT2ASMN1; SMN2MAPT | |
| SCHEMBL12758412 | 0.73 | MEN1 (0.38) | ALDH1A1HPGDKDM4EKMT2AF2 | |
| SCHEMBL12758406 | 0.72 | ALDH1A1 (0.45) | ALDH1A1HPGDKDM4EKMT2AF2 | |
| SCHEMBL12758394 | 0.72 | ELANE (0.47) | ALDH1A1HPGDKDM4EKMT2AMAPT | |
| SCHEMBL14417715 | 0.71 | ALDH1A1 (0.94) | ALDH1A1HPGDKDM4EKMT2AF2 | |
| SCHEMBL23040964 | 0.71 | ALDH1A1 (0.64) | ALDH1A1HPGDKDM4EKMT2AF2 | |
| SCHEMBL7193264 | 0.70 | NOTUM (0.47) | ALDH1A1HPGDKDM4ESMN1; SMN2MAPT | |
| SCHEMBL12010961 | 0.69 | ALDH1A1 (1.00) | ALDH1A1HPGDKDM4EKMT2AF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070219343-A1 | Isobenzoxazinones And Their Use As Ultraviolet Light Absorbers | CLARIANT INTERNATIONAL LTD. (CH) | 2007-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070219343-A1 | Isobenzoxazinones And Their Use As Ultraviolet Light Absorbers | CYP1B1, UGT1A7, UGT2B17 | ALDH1A1 41/4885HPGD 171/4885KDM4E 2062/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.