Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | C1R | P00736 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | APEX1 | P27695 | 2/20 | 0.36 |
| ▸ | CTSG | P08311 | 2/20 | 0.35 |
| ▸ | KLK7 | P49862 | 2/20 | 0.35 |
| ▸ | KLK14 | Q9P0G3 | 2/20 | 0.35 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL914362 | 0.83 | ALDH1A1 (0.67) | ALDH1A1KDM4EC1RMEN1KMT2A | |
| SCHEMBL12352147 | 0.75 | APEX1 (0.59) | ALDH1A1KDM4EC1RMEN1KMT2A | |
| SCHEMBL12758412 | 0.74 | MEN1 (0.38) | ALDH1A1KDM4EC1RMEN1KMT2A | |
| SCHEMBL7191472 | 0.74 | IKBKB (0.42) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL22952939 | 0.73 | KDM4E (0.45) | ALDH1A1KDM4EC1RMEN1KMT2A | |
| SCHEMBL12758394 | 0.73 | ELANE (0.47) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL14417717 | 0.72 | ALDH1A1 (0.52) | ALDH1A1KDM4EC1RMEN1KMT2A | |
| SCHEMBL7193264 | 0.71 | NOTUM (0.47) | ALDH1A1KDM4EC1RHPGDSMN1; SMN2 | |
| SCHEMBL28841248 | 0.69 | ALDH1A1 (0.44) | ALDH1A1KDM4EHPGDSMN1; SMN2MAPT | |
| SCHEMBL12758414 | 0.69 | ALDH1A1 (0.49) | ALDH1A1KDM4EC1RMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7897761-B2 | Heterocyclic compound | FUJIFILM CORPORATION (JP) | 2011-03-01 | — | — | US | disclosed |
| US-7897761-B2 | Heterocyclic compound | FUJIFILM CORPORATION (JP) | 2011-03-01 | — | — | US | disclosed |
| US-20100004439-A1 | Heterocyclic Compound | FUJIFLM CORPORATION (JP) | 2010-01-07 | — | — | US | disclosed |
| US-20100004439-A1 | Heterocyclic Compound | FUJIFLM CORPORATION (JP) | 2010-01-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100004439-A1 | Heterocyclic Compound | PTGER1, CYP1A1, ALOX12 | ALDH1A1 1205/4885KDM4E 2305/4885C1R 959/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.