Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 13/20 | 0.53 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.47 |
| ▸ | CDK2 | P24941 | 5/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.41 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13121559 | 0.91 | GSK3B (0.65) | GSK3BCDK2CCNE1 | |
| SCHEMBL12954511 | 0.91 | GSK3B (0.53) | GSK3BCHEK1CDK2CCNE1CCNA2 | |
| SCHEMBL14545949 | 0.87 | GSK3B (0.60) | GSK3BCHEK1CDK2CCNE1 | |
| SCHEMBL14418650 | 0.86 | GSK3B (0.61) | GSK3BCHEK1CDK2CCNE1 | |
| SCHEMBL13121524 | 0.86 | GSK3B (0.64) | GSK3BCDK2CCNE1 | |
| SCHEMBL13121525 | 0.86 | GSK3B (0.64) | GSK3BCDK2CCNE1 | |
| SCHEMBL14418651 | 0.86 | GSK3B (0.55) | GSK3BCHEK1CDK2CCNE1CCNA2 | |
| SCHEMBL14607246 | 0.85 | GSK3B (0.53) | GSK3BCHEK1CDK2CCNE1CCNA2 | |
| SCHEMBL14545280 | 0.84 | GSK3B (0.51) | GSK3BCHEK1CDK2CCNE1 | |
| SCHEMBL14545947 | 0.84 | GSK3B (0.56) | GSK3BCHEK1CDK2CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070225270-A1 | Pyrazolopyrimidines as cyclin dependent kinase inhibitors | SCHERING CORPORATION | 2007-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070225270-A1 | Pyrazolopyrimidines as cyclin dependent kinase inhibitors | CDK2, CDKN1A, CDK1 | GSK3B 749/4885CHEK1 58/4885CDK2 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.