Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14419295 | 0.91 | MAPT (0.50) | ALDH1A1TDP1L3MBTL1MAPTGAA | |
| SCHEMBL14419279 | 0.90 | MAPT (0.47) | ALDH1A1TDP1L3MBTL1MAPTGAA | |
| SCHEMBL14419576 | 0.90 | SLC2A1 (0.45) | ALDH1A1TDP1L3MBTL1MAPTGAA | |
| SCHEMBL14419306 | 0.89 | ALDH1A1 (0.50) | ALDH1A1TDP1L3MBTL1MAPTGAA | |
| SCHEMBL14419300 | 0.87 | MAPT (0.47) | ALDH1A1TDP1L3MBTL1MAPTGAA | |
| SCHEMBL14419477 | 0.86 | MAPT (0.50) | ALDH1A1TDP1L3MBTL1MAPTGAA | |
| SCHEMBL14419325 | 0.85 | HPGD (0.58) | ALDH1A1TDP1L3MBTL1MAPTGAA | |
| SCHEMBL14419423 | 0.85 | GAA (0.46) | ALDH1A1TDP1L3MBTL1MAPTGAA | |
| SCHEMBL14419282 | 0.84 | MAPT (0.48) | ALDH1A1TDP1L3MBTL1MAPTGAA | |
| SCHEMBL14419692 | 0.84 | PTGDR2 (0.50) | ALDH1A1TDP1L3MBTL1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7273863-B1 | Benzophenones as inhibitors of reverse transcriptase | SMITHKLINE BEECHAM CORPORATION (US) | 2007-09-25 | — | — | US | disclosed |