Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | VNN1 | O95497 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14419687 | 0.90 | SLC2A1 (0.46) | SLC2A1ALDH1A1TDP1L3MBTL1MAPT | |
| SCHEMBL13743326 | 0.90 | MRGPRX4 (0.44) | SLC2A1MAPTPTGDR2MRGPRX4LMNA | |
| SCHEMBL14419231 | 0.90 | ALDH1A1 (0.47) | ALDH1A1TDP1L3MBTL1MAPTTHRB | |
| SCHEMBL12328443 | 0.86 | PTGDR2 (0.54) | SLC2A1TDP1MAPTPTGDR2MRGPRX4 | |
| SCHEMBL14419295 | 0.83 | MAPT (0.50) | ALDH1A1TDP1L3MBTL1MAPTTHRB | |
| SCHEMBL14419279 | 0.82 | MAPT (0.47) | ALDH1A1TDP1L3MBTL1MAPTTHRB | |
| SCHEMBL12328442 | 0.82 | POLB (0.49) | MAPTMRGPRX4LMNA | |
| SCHEMBL14419306 | 0.81 | ALDH1A1 (0.50) | ALDH1A1TDP1L3MBTL1MAPTTHRB | |
| SCHEMBL14419300 | 0.80 | MAPT (0.47) | ALDH1A1TDP1L3MBTL1MAPTTHRB | |
| SCHEMBL14419477 | 0.79 | MAPT (0.50) | ALDH1A1TDP1L3MBTL1MAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7273863-B1 | Benzophenones as inhibitors of reverse transcriptase | SMITHKLINE BEECHAM CORPORATION (US) | 2007-09-25 | — | — | US | disclosed |