Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | PTGDR2 | Q9Y5Y4 | 14/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.46 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14419259 | 0.85 | MAPT (0.46) | TDP1PTGDR2MAPTKCNMA1CYP2C9 | |
| SCHEMBL5623703 | 0.84 | NPC1 (0.50) | MAPTKCNMA1 | |
| SCHEMBL14419236 | 0.83 | KCNMA1 (0.64) | TDP1MAPTKCNMA1CYP2C9 | |
| SCHEMBL4627690 | 0.82 | TDP1 (0.70) | TDP1PTGDR2MAPTTSHRPTGDR | |
| SCHEMBL21276512 | 0.80 | PTGDR2 (0.62) | TDP1PTGDR2MAPTTSHRPTGDR | |
| SCHEMBL14419330 | 0.79 | CYP2C9 (0.71) | TDP1PTGDR2MAPTTSHRCYP2C9 | |
| SCHEMBL14419230 | 0.77 | KCNMA1 (0.60) | TDP1MAPTKCNMA1 | |
| SCHEMBL9209426 | 0.77 | TDP1 (0.62) | TDP1PTGDR2MAPTTSHRPTGDR | |
| SCHEMBL4143335 | 0.76 | TDP1 (0.70) | TDP1PTGDR2MAPTTSHRPTGDR | |
| SCHEMBL14419338 | 0.76 | PTGDR2 (0.55) | TDP1PTGDR2MAPTTSHRPTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7273863-B1 | Benzophenones as inhibitors of reverse transcriptase | SMITHKLINE BEECHAM CORPORATION (US) | 2007-09-25 | — | — | US | disclosed |