Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 5/20 | 0.60 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.46 |
| ▸ | GCK | P35557 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 2/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | RBBP9 | O75884 | 1/20 | 0.42 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL343646 | 0.84 | GCK (0.61) | KCNMA1PLA2G7GCKCASP3SENP8 | |
| SCHEMBL28566981 | 0.83 | KCNMA1 (0.59) | KCNMA1CA1CA2GCKCASP3 | |
| SCHEMBL22823848 | 0.82 | HPGD (0.59) | KCNMA1PLA2G7CASP1LMNAKMT2A | |
| SCHEMBL13252870 | 0.81 | PLA2G7 (0.49) | KCNMA1PLA2G7GCKCASP3SENP8 | |
| SCHEMBL14419236 | 0.80 | KCNMA1 (0.64) | KCNMA1CASP3SENP8SENP7SENP6 | |
| SCHEMBL2616490 | 0.79 | KMT2A (0.65) | KCNMA1GCKCASP3SENP8SENP7 | |
| SCHEMBL3830939 | 0.79 | MAPT (0.57) | PLA2G7CASP3SENP8SENP7SENP6 | |
| SCHEMBL14419260 | 0.77 | TDP1 (0.52) | KCNMA1MAPTTDP1 | |
| SCHEMBL3835536 | 0.77 | CYP1A2 (0.61) | PLA2G7CASP3SENP8SENP7SENP6 | |
| SCHEMBL29752158 | 0.76 | PLA2G7 (0.56) | CA1CA2PLA2G7CASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7273863-B1 | Benzophenones as inhibitors of reverse transcriptase | SMITHKLINE BEECHAM CORPORATION (US) | 2007-09-25 | — | — | US | disclosed |