Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 16/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14419420 | 0.88 | PTGDR2 (0.65) | PTGDR2CYP2C9 | |
| SCHEMBL14419283 | 0.86 | PTGDR2 (0.61) | PTGDR2CYP2C9TDP1TSHRMAPT | |
| SCHEMBL14419238 | 0.86 | ALDH1A1 (0.47) | PTGDR2TDP1MAPT | |
| SCHEMBL8398940 | 0.84 | PTGDR2 (0.70) | PTGDR2TDP1TSHRMAPT | |
| SCHEMBL14419292 | 0.82 | PTGDR2 (0.56) | PTGDR2CYP2C9TDP1TSHRMAPT | |
| SCHEMBL14419544 | 0.82 | PTGDR2 (0.68) | PTGDR2CYP2C9TDP1TSHRMAPT | |
| SCHEMBL14419280 | 0.82 | PTGDR2 (0.56) | PTGDR2CYP2C9TDP1TSHRMAPT | |
| SCHEMBL14419418 | 0.81 | PTGDR2 (0.51) | PTGDR2CYP2C9 | |
| SCHEMBL9209426 | 0.80 | TDP1 (0.62) | PTGDR2TDP1TSHRMAPT | |
| SCHEMBL4627690 | 0.79 | TDP1 (0.70) | PTGDR2CYP2C9TDP1TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7273863-B1 | Benzophenones as inhibitors of reverse transcriptase | SMITHKLINE BEECHAM CORPORATION (US) | 2007-09-25 | — | — | US | disclosed |