Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | PKM | P14618 | 3/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.56 |
| ▸ | CRHBP | P24387 | 1/20 | 0.56 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6034118 | 0.87 | PKM (0.58) | ALDH1A1PKMMEN1KMT2ARAB9A | |
| SCHEMBL5627956 | 0.86 | SMN1; SMN2 (0.69) | ALDH1A1MEN1KMT2ALMNATSHR | |
| SCHEMBL9796209 | 0.85 | ALDH1A1 (0.67) | ALDH1A1PKMMEN1KMT2ARAB9A | |
| SCHEMBL17790336 | 0.83 | ALDH1A1 (0.66) | ALDH1A1PKMMEN1KMT2ALMNA | |
| SCHEMBL29859274 | 0.83 | ALDH1A1 (0.66) | ALDH1A1PKMMEN1KMT2ALMNA | |
| SCHEMBL14501508 | 0.82 | MEN1 (0.66) | ALDH1A1PKMMEN1KMT2ALMNA | |
| SCHEMBL16492273 | 0.82 | MEN1 (0.66) | ALDH1A1PKMMEN1KMT2ALMNA | |
| SCHEMBL20526493 | 0.81 | KDM4E (0.63) | ALDH1A1MEN1KMT2ARAB9AUSP2 | |
| SCHEMBL30872560 | 0.81 | HTT (0.51) | ALDH1A1PKMMEN1KMT2AMCOLN3 | |
| SCHEMBL16492268 | 0.80 | ALDH1A1 (0.71) | ALDH1A1PKMMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7273863-B1 | Benzophenones as inhibitors of reverse transcriptase | SMITHKLINE BEECHAM CORPORATION (US) | 2007-09-25 | — | — | US | disclosed |