Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR8 | P51685 | 1/20 | 0.61 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.54 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.54 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.54 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.54 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | PARG | Q86W56 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14419684 | 0.83 | POLB (0.64) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL14419466 | 0.82 | BACE1 (0.55) | CCR8PPARGALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL14419634 | 0.80 | PPARG (0.53) | PDK1PDK2PDK3PDK4PPARG | |
| SCHEMBL14419470 | 0.80 | ALDH1A1 (0.57) | PPARGMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL14419631 | 0.78 | RAB9A (0.68) | KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL14419602 | 0.77 | PARG (0.55) | CCR8MEN1KMT2AALDH1A1CYP2C9 | |
| SCHEMBL24997782 | 0.76 | CCR8 (1.00) | CCR8 | |
| SCHEMBL4397776 | 0.76 | MEN1 (0.68) | MEN1KMT2AALDH1A1CYP2C9HPGD | |
| SCHEMBL4397778 | 0.76 | MEN1 (0.68) | MEN1KMT2AALDH1A1CYP2C9HPGD | |
| SCHEMBL14419664 | 0.76 | ALDH1A1 (0.60) | KMT2AALDH1A1SMN1; SMN2LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7273863-B1 | Benzophenones as inhibitors of reverse transcriptase | SMITHKLINE BEECHAM CORPORATION (US) | 2007-09-25 | — | — | US | disclosed |