Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | EEF2K | O00418 | 3/20 | 0.42 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14419655 | 0.79 | ALDH1A1 (0.48) | ALDH1A1ATML3MBTL1KMT2APOLB | |
| SCHEMBL15388168 | 0.78 | ALDH1A1 (0.53) | ALDH1A1ATML3MBTL1KMT2AEEF2K | |
| SCHEMBL15388169 | 0.78 | ALDH1A1 (0.53) | ALDH1A1ATML3MBTL1KMT2AEEF2K | |
| SCHEMBL15387917 | 0.78 | ALDH1A1 (0.53) | ALDH1A1ATML3MBTL1KMT2APOLB | |
| SCHEMBL15387918 | 0.78 | ALDH1A1 (0.53) | ALDH1A1ATML3MBTL1KMT2APOLB | |
| SCHEMBL7870945 | 0.77 | POLB (0.53) | ALDH1A1ATML3MBTL1KMT2APOLB | |
| SCHEMBL1287300 | 0.76 | MAPT (0.57) | ALDH1A1ATML3MBTL1KMT2AKCNA5 | |
| SCHEMBL1287270 | 0.76 | MAPT (0.57) | ALDH1A1ATML3MBTL1KMT2AKCNA5 | |
| SCHEMBL1287380 | 0.76 | ALDH1A1 (0.56) | ALDH1A1ATML3MBTL1KMT2AEEF2K | |
| SCHEMBL15388076 | 0.76 | ALDH1A1 (0.56) | ALDH1A1ATML3MBTL1KMT2AEEF2K |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7273863-B1 | Benzophenones as inhibitors of reverse transcriptase | SMITHKLINE BEECHAM CORPORATION (US) | 2007-09-25 | — | — | US | disclosed |