Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | CASP7 | P55210 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8572921 | 0.79 | ALDH1A1 (0.63) | HDAC1ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL8328245 | 0.79 | HDAC1 (0.76) | HDAC1ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL5903723 | 0.79 | HDAC1 (1.00) | HDAC1ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL8571740 | 0.78 | ALDH1A1 (0.61) | HDAC1ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL13857534 | 0.75 | HDAC1 (0.73) | HDAC1ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL13930616 | 0.74 | HDAC1 (0.58) | HDAC1ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL3054745 | 0.74 | ALDH1A1 (0.69) | HDAC1ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL7870469 | 0.73 | ALDH1A1 (0.89) | HDAC1ALDH1A1KDM4ELMNAGAA | |
| Potassium Ion SCHEMBL25278002 | 0.72 | ALDH1A1 (0.67) | HDAC1ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL15803999 | 0.72 | ALDH1A1 (0.67) | HDAC1ALDH1A1KDM4ELMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7268115-B2 | Cyclic peptides; three-dimensional structures; screening; anticancer agents; angiogenesis inhibitors; drug delivery | ADHEREX TECHNOLOGIES, INC. (CA) | 2007-09-11 | — | — | US | disclosed |