Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 5/20 | 0.46 |
| ▸ | PPARG | P37231 | 4/20 | 0.46 |
| ▸ | XIAP | P98170 | 1/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LPL | P06858 | 2/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | YWHAG | P61981 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14420100 | 0.91 | SLC7A5 (0.43) | PPARAPPARGCYP4F2CYP4A11SLC7A5 | |
| SCHEMBL14420169 | 0.90 | ALDH1A1 (0.50) | PPARAPPARGXIAPLMNAMAPT | |
| SCHEMBL14420220 | 0.90 | PPARA (0.47) | PPARAPPARGXIAPCYP4F2CYP4A11 | |
| SCHEMBL14420058 | 0.85 | SLC7A5 (0.44) | LMNASLC7A5ALDH1A1 | |
| SCHEMBL11633852 | 0.83 | ALDH1A1 (0.61) | PPARAPPARGLMNAMAPTALDH1A1 | |
| SCHEMBL1630566 | 0.82 | PPARA (0.65) | PPARAPPARGCYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL14420121 | 0.82 | SLC7A5 (0.55) | PPARAPPARGCYP4F2CYP4A11SLC7A5 | |
| SCHEMBL14420170 | 0.81 | YWHAG (0.42) | PPARAPPARGCYP4F2CYP4A11SLC7A5 | |
| SCHEMBL14420143 | 0.81 | ALDH1A1 (0.53) | LMNAMAPTSLC7A5ALDH1A1YWHAG | |
| SCHEMBL14420084 | 0.80 | TSHR (0.43) | PPARAPPARGXIAPSLC7A5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070225303-A1 | 8-Oxoadenine Compound | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2007-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070225303-A1 | 8-Oxoadenine Compound | TLR7, CCR8, TLR8 | PPARA 2948/4885PPARG 2374/4885XIAP 617/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.