Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | PAM | P19021 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.42 |
| ▸ | YWHAG | P61981 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14420169 | 0.91 | ALDH1A1 (0.50) | ALDH1A1MAPK1L3MBTL1PAMSMN1; SMN2 | |
| SCHEMBL14420170 | 0.91 | YWHAG (0.42) | ALDH1A1MAPK1L3MBTL1PAMALOX5 | |
| SCHEMBL14420100 | 0.89 | SLC7A5 (0.43) | ALDH1A1MAPK1L3MBTL1PAMALOX5 | |
| SCHEMBL2630609 | 0.87 | PPARA (0.51) | ALDH1A1MAPK1L3MBTL1PAMSMN1; SMN2 | |
| SCHEMBL14420204 | 0.87 | ALDH1A1 (0.56) | ALDH1A1MAPK1L3MBTL1PAMSMN1; SMN2 | |
| SCHEMBL14420123 | 0.82 | SLC7A5 (0.57) | ALDH1A1TSHRSLC7A5MAPTLMNA | |
| SCHEMBL14420220 | 0.82 | PPARA (0.47) | ALDH1A1MAPTLMNAYWHAGMTNR1A | |
| SCHEMBL14420107 | 0.81 | PPARA (0.46) | ALDH1A1SLC7A5MAPTLMNAYWHAG | |
| SCHEMBL11633852 | 0.81 | ALDH1A1 (0.61) | ALDH1A1MAPK1L3MBTL1PAMTSHR | |
| SCHEMBL18331645 | 0.80 | ALDH1A1 (0.63) | ALDH1A1MAPK1L3MBTL1PAMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070225303-A1 | 8-Oxoadenine Compound | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2007-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070225303-A1 | 8-Oxoadenine Compound | TLR7, CCR8, TLR8 | ALDH1A1 1017/4885MAPK1 2737/4885L3MBTL1 621/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.