Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9294282 | 0.82 | GAA (0.40) | GAAALDH1A1LMNAHSD17B10TDP1 | |
| SCHEMBL18084166 | 0.80 | GAA (0.36) | GAAALDH1A1LMNAHSD17B10TDP1 | |
| SCHEMBL859738 | 0.79 | — | — | |
| SCHEMBL28367893 | 0.77 | CYP4F2 (0.36) | GAAALDH1A1LMNAHSD17B10ELANE | |
| SCHEMBL13156166 | 0.76 | GAA (0.38) | GAAALDH1A1LMNATDP1 | |
| SCHEMBL13781377 | 0.76 | GAA (0.34) | GAA | |
| SCHEMBL8209412 | 0.76 | CYP4F2 (0.35) | GAAALDH1A1LMNAHSD17B10ELANE | |
| SCHEMBL193212 | 0.76 | CYP4F2 (0.35) | GAAALDH1A1LMNAHSD17B10ELANE | |
| SCHEMBL27437465 | 0.76 | CYP4F2 (0.52) | GAAALDH1A1LMNAHSD17B10ELANE | |
| SCHEMBL22797630 | 0.73 | GAA (0.34) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007098826-A2 | MODULATORS OF ALPHA7 NICOTINIC ACETYLCHOLINE RECEPTORS AND THERAPEUTIC USES THEREOF | SIENA BIOTECH S.P.A. (IT) | 2007-09-07 | — | — | WO | disclosed |