Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9294282 | 0.86 | GAA (0.40) | GAAALDH1A1LMNAHSD17B10TDP1 | |
| SCHEMBL14420197 | 0.80 | GAA (0.38) | GAAALDH1A1LMNAHSD17B10TDP1 | |
| SCHEMBL13156166 | 0.80 | GAA (0.38) | GAAALDH1A1LMNATDP1 | |
| SCHEMBL9710090 | 0.79 | TSHR (0.36) | ALDH1A1TDP1 | |
| SCHEMBL269270 | 0.77 | — | — | |
| SCHEMBL20321520 | 0.77 | LMNA (0.30) | LMNAHSD17B10 | |
| SCHEMBL19493224 | 0.77 | KDM4E (0.44) | GAAALDH1A1 | |
| SCHEMBL22797630 | 0.77 | GAA (0.34) | GAA | |
| SCHEMBL21743240 | 0.77 | ALDH1A1 (0.30) | GAAALDH1A1TDP1 | |
| SCHEMBL18132831 | 0.77 | TSHR (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3156525-A1 | YARN OF POLYOLEFIN FIBERS | DSM IP Assets B.V. (NL) | 2017-04-19 | — | — | EP | disclosed |
| US-9434761-B2 | Tripeptide epoxy ketone protease inhibitors | ONYX THERAPEUTICS, INC. (US) | 2016-09-06 | — | — | US | disclosed |