Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27339480 | 0.87 | GAA (0.33) | GAAALDH1A1MAPTPTGS1LMNA | |
| SCHEMBL13156166 | 0.87 | GAA (0.38) | GAAALDH1A1MAPTPTGS1LMNA | |
| SCHEMBL18084166 | 0.86 | GAA (0.36) | GAAALDH1A1LMNAHSD17B10TDP1 | |
| SCHEMBL10086138 | 0.84 | GAA (0.34) | GAAALDH1A1TDP1 | |
| SCHEMBL22797630 | 0.84 | GAA (0.34) | GAA | |
| SCHEMBL19493224 | 0.84 | KDM4E (0.44) | GAAALDH1A1MAPTPTGS1 | |
| SCHEMBL14420197 | 0.82 | GAA (0.38) | GAAALDH1A1LMNAHSD17B10TDP1 | |
| SCHEMBL18011682 | 0.82 | KDM4E (0.48) | GAAALDH1A1MAPTPTGS1TSHR | |
| SCHEMBL673097 | 0.81 | GAA (0.35) | GAAALDH1A1MAPTPTGS1TDP1 | |
| SCHEMBL20016625 | 0.80 | ALDH1A1 (0.34) | GAAALDH1A1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE34640-E | Polymerizing isobutylene, adding monomer to make block polymer; metal halide, initiator and electron pair doner solvent | UNIVERSITY OF AKRON (US) | 1994-06-14 | — | — | US | claimed |
| WO-1991011468-A1 | NEW THERMOPLASTIC ELASTOMERS | THE UNIVERSITY OF AKRON (US) | 1991-08-08 | — | — | WO | claimed |
| US-4946899-A | CARBOCATIONIC POLYMERIZATION INVOLVING HOMOPOLYMERIZATION OF ELASTOMER FOLLOWED BY COPOLYMERIZATION TO ADD GLASSY SEGMENTS; FORMING LIVING POLYMERS WITH A METAL HALIDE, PROMOTER AND SOLVENT MIXTURE | THE UNIVERSITY OF AKRON (US) | 1990-08-07 | — | — | US | claimed |
| CN-102356114-B | Amine-terminated telechelic polymers and precursors thereto and methods for their preparation | CHEVRON ORONITE CO | 2014-06-25 | — | — | CN | disclosed |