Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 1/20 | 0.45 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.45 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.45 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.45 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.45 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | CTSG | P08311 | 1/20 | 0.41 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5765424 | 0.85 | PSEN1 (0.42) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL5765432 | 0.85 | PSEN1 (0.42) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL29589736 | 0.84 | NPSR1 (0.53) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL6649629 | 0.84 | NPSR1 (0.53) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL6649624 | 0.84 | NPSR1 (0.53) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL5765672 | 0.83 | SMN1; SMN2 (0.49) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL9977406 | 0.83 | HTR2C (0.54) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL5765666 | 0.83 | SMN1; SMN2 (0.49) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL10289210 | 0.81 | HTR2C (0.44) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL7576828 | 0.80 | PDK1 (0.40) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7265105-B2 | Pyrrolobenzodiazepines | SPIROGEN LIMITED (GB) | 2007-09-04 | — | — | US | disclosed |