Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MET | P08581 | 3/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18948481 | 0.80 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2LMNAAKR1C3AKR1C2 | |
| SCHEMBL29473917 | 0.75 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2LMNAAKR1C3AKR1C2 | |
| SCHEMBL20309118 | 0.75 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2LMNAAKR1C3AKR1C2 | |
| SCHEMBL114725 | 0.75 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2LMNAAKR1C3AKR1C2 | |
| Bicarbonate SCHEMBL28288596 | 0.75 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2LMNAAKR1C3AKR1C2 | |
| Methane SCHEMBL28862287 | 0.74 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2LMNAAKR1C3AKR1C2 | |
| SCHEMBL18948483 | 0.74 | MET (0.45) | ALDH1A1SMN1; SMN2LMNAPPARGPPARA | |
| SCHEMBL1951478 | 0.73 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2LMNAAKR1C3AKR1C2 | |
| SCHEMBL19003687 | 0.73 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2LMNAPPARGPPARA | |
| SCHEMBL5778369 | 0.73 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2LMNAAKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011026085-A2 | REACTIVE CYANINE COMPOUNDS | PROMEGA CORPORATION (US) | 2011-03-03 | — | — | WO | disclosed |