Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.49 |
| ▸ | GLS | O94925 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MET | P08581 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3158800 | 0.80 | DAO (0.51) | DAOGLSHDAC3CNR1CNR2 | |
| SCHEMBL27947601 | 0.80 | CYP1A2 (0.57) | DAOGLSHDAC3NPC1POLB | |
| SCHEMBL21171893 | 0.80 | TRPV1 (0.46) | HDAC3RAB9AHDAC6 | |
| SCHEMBL21171904 | 0.79 | HDAC1 (0.56) | HDAC3 | |
| SCHEMBL4195374 | 0.79 | ALDH1A1 (0.50) | DAOCNR1CNR2NPC1POLB | |
| SCHEMBL5535997 | 0.79 | DAO (0.50) | DAOGLSHDAC3CNR1CNR2 | |
| SCHEMBL3711594 | 0.79 | DAO (0.50) | DAOGLSHDAC3CNR1CNR2 | |
| SCHEMBL4020874 | 0.79 | DAO (0.56) | DAOGLSHDAC3CNR1CNR2 | |
| SCHEMBL934234 | 0.78 | HDAC3 (0.50) | DAOGLSHDAC3NPC1POLB | |
| SCHEMBL12251092 | 0.78 | L3MBTL1 (0.47) | DAOGLSHDAC3CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011026085-A2 | REACTIVE CYANINE COMPOUNDS | PROMEGA CORPORATION (US) | 2011-03-03 | — | — | WO | disclosed |