Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 11/20 | 0.49 |
| ▸ | NPC1 | O15118 | 9/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL155142 | 0.79 | RAB9A (0.57) | RAB9ANPC1SMN1; SMN2PKMMAPT | |
| SCHEMBL16238270 | 0.77 | RAB9A (0.64) | RAB9ANPC1SMN1; SMN2PKMMAPT | |
| SCHEMBL22467996 | 0.73 | RAB9A (0.47) | RAB9ANPC1SMN1; SMN2PKMMAPT | |
| SCHEMBL2631604 | 0.73 | RAB9A (0.56) | RAB9ANPC1SMN1; SMN2PKMMAPT | |
| SCHEMBL27606981 | 0.73 | RAB9A (0.56) | RAB9ANPC1SMN1; SMN2PKMMAPT | |
| SCHEMBL10671313 | 0.73 | MAPT (0.54) | RAB9ANPC1SMN1; SMN2PKMMAPT | |
| SCHEMBL11219074 | 0.72 | RAB9A (0.58) | RAB9ANPC1SMN1; SMN2PKMMAPT | |
| Bromide SCHEMBL9638376 | 0.72 | RAB9A (0.46) | RAB9ANPC1SMN1; SMN2PKMMAPT | |
| SCHEMBL2837341 | 0.71 | MAPT (0.55) | RAB9ANPC1SMN1; SMN2PKMMAPT | |
| SCHEMBL12599387 | 0.71 | LCK (0.54) | RAB9ANPC1SMN1; SMN2PKMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007107373-A1 | SUBSTITUTED TETRAHYDROISOQUINOLINE COMPOUNDS, THEIR PREPARATION AND USE IN MEDICAMENTS | LABORATORIOS DEL DR. ESTEVE S.A. (DE) | 2007-09-27 | — | — | WO | disclosed |