Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 12/20 | 0.56 |
| ▸ | NPC1 | O15118 | 10/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16238270 | 0.83 | RAB9A (0.64) | RAB9ANPC1SMN1; SMN2PKMMAPT | |
| SCHEMBL10812910 | 0.83 | RAB9A (0.68) | RAB9ANPC1SMN1; SMN2PKMMAPT | |
| SCHEMBL155142 | 0.82 | RAB9A (0.57) | RAB9ANPC1SMN1; SMN2PKMMAPT | |
| SCHEMBL2837341 | 0.81 | MAPT (0.55) | RAB9ANPC1SMN1; SMN2PKMMAPT | |
| SCHEMBL27606981 | 0.80 | RAB9A (0.56) | RAB9ANPC1SMN1; SMN2PKMMAPT | |
| SCHEMBL11219074 | 0.78 | RAB9A (0.58) | RAB9ANPC1SMN1; SMN2PKMMAPT | |
| SCHEMBL12599387 | 0.77 | LCK (0.54) | RAB9ANPC1SMN1; SMN2PKMMAPT | |
| SCHEMBL11231406 | 0.77 | RAB9A (0.57) | RAB9ANPC1SMN1; SMN2PKMMAPT | |
| SCHEMBL11485186 | 0.77 | RAB9A (0.53) | RAB9ANPC1SMN1; SMN2PKMMAPT | |
| SCHEMBL2837345 | 0.77 | MAPT (0.55) | RAB9ANPC1SMN1; SMN2PKMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120094948-A1 | Analogous Compounds of 6-Thioguanosine Triphosphate, their use in Medical Fields and Processes for their Preparation | GIULIANI INTERNATIONAL LIMITED | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120094948-A1 | Analogous Compounds of 6-Thioguanosine Triphosphate, their use in Medical Fields and Processes for their Preparation | TPMT, MTAP, G6PD | RAB9A 2759/4885NPC1 3105/4885SMN1; SMN2 2842/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.